Improving blood sugar control in type 2 diabetes
CHANGING THE NATURAL HISTORY OF TYPE 2 DIABETES – “CHANGE” STUDY
This study is looking for adults with early type 2 diabetes to see if keeping their blood sugar levels normal can help prevent the condition from getting worse, with some participants receiving standard care and others getting extra treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11086665 on NIH RePORTER |
What this research studies
This research aims to improve blood sugar levels in adults with early type 2 diabetes by maintaining normal glucose levels, which may prevent the typical worsening of the condition. The study will involve three groups of participants, some receiving standard care and others receiving intensified treatment to keep their blood sugar normal. By focusing on early intervention and using FDA-approved medications, the research seeks to assess the effects on beta-cell function and related complications. Participants will be monitored for changes in their diabetes progression and overall health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have early-stage type 2 diabetes with an A1c level between 6.0% and 6.9%.
Not a fit: Patients with advanced type 2 diabetes or those not meeting the specified A1c criteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management of type 2 diabetes and reduce the risk of complications for patients.
How similar studies have performed: Previous studies have shown that early interventions in diabetes management can significantly reduce the progression of the disease, suggesting that this approach may also be effective.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Phillips, Lawrence S — Emory University
- Study coordinator: Phillips, Lawrence S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.