Improving blood sugar control during exercise for people with Type 1 diabetes.
Limiting Dysglycemia Around Physical Activity for People with Type 1 Diabetes Using Activity-Aware Automated Insulin Delivery – the APEX Project.
['FUNDING_R01'] · UNIVERSITY OF VIRGINIA · NIH-10855771
This study is looking for ways to help people with Type 1 diabetes manage their insulin better during exercise, so they can feel more comfortable being active without worrying about low blood sugar.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF VIRGINIA (nih funded) |
| Locations | 1 site (CHARLOTTESVILLE, UNITED STATES) |
| Trial ID | NIH-10855771 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing glycemic control for individuals with Type 1 diabetes during physical activity by testing innovative methods to adjust insulin delivery. The study will explore three approaches: real-time adjustments based on insulin sensitivity changes, accounting for previous activity's impact on insulin needs, and predicting future activity based on past patterns. By integrating these methods into a fully closed-loop automated insulin delivery system, participants can enjoy more spontaneous physical activity without the constant need to manage their insulin levels. This project aims to alleviate the fear of hypoglycemia that often discourages exercise among people with diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Type 1 diabetes who are interested in improving their blood sugar management during exercise.
Not a fit: Patients with Type 2 diabetes or those who do not engage in physical activity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enable people with Type 1 diabetes to engage in physical activity more freely and safely, improving their overall health and quality of life.
How similar studies have performed: Previous research has shown promise in using automated insulin delivery systems to improve glycemic control, making this approach both innovative and grounded in successful methodologies.
Where this research is happening
CHARLOTTESVILLE, UNITED STATES
- UNIVERSITY OF VIRGINIA — CHARLOTTESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BRETON, MARC D — UNIVERSITY OF VIRGINIA
- Study coordinator: BRETON, MARC D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Brittle Diabetes Mellitus