NIH-funded research R01 grant

Improving blood pressure control in rural South Africa

Official title: Implementation of a Combination Intervention for Sustainable Blood Pressure Control in Rural KwaZulu-Natal, South Africa (IMPACT-BP)

Funded at Kwazulu-Natal Research Institute Tb-HIV · NIH-10906031 · Data updated 2026-11-12

This study is looking at ways to help people in rural KwaZulu-Natal, South Africa, better manage their high blood pressure, which can lead to serious health issues like strokes and heart disease, by finding out what challenges they face and how to improve their care.

More Blood Pressure research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionKwazulu-Natal Research Institute Tb-HIV
NIH-funded
Lab location1 site (Durban, SOUTH AFRICA)
Project startSeptember 4, 2020
Project endAugust 31, 2025
Funding year2024
Award (this year)$572,149
NIH project number5R01HL144848-05
Project IDNIH-10906031 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults over 18 years old living in rural KwaZulu-Natal with uncontrolled hypertension.

Less likely to help

Patients who are already effectively managing their hypertension or those living outside the targeted rural areas may not benefit from this research.

What this research studies

This research focuses on addressing uncontrolled hypertension, a major risk factor for stroke and heart disease, in rural KwaZulu-Natal, South Africa. It aims to implement a combination of innovative and cost-effective interventions to improve hypertension care and management in a resource-limited setting. The study involves mixed-methods approaches, including qualitative interviews with patients and healthcare professionals, to identify barriers to effective hypertension care and develop best practices for implementation. By enhancing patient self-efficacy and addressing structural barriers, the research seeks to increase the number of individuals receiving effective treatment for hypertension.

Why it matters

Potential benefit: If successful, this research could significantly reduce the incidence of stroke and heart disease by improving blood pressure management in rural populations.

How similar studies have gone: Previous research has shown success in implementing similar interventions for hypertension control in other resource-limited settings, indicating potential for positive outcomes in this study.

Where this research is happening

  • Kwazulu-Natal Research Institute Tb-HIV
    Durban, South Africa
    Active

Researchers

  • Principal investigator: Siedner, Mark J — Kwazulu-Natal Research Institute Tb-HIV
  • Study coordinator: Siedner, Mark J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.