NIH-funded research NIH-funded research

Improving blood health in adolescents before scoliosis surgery

Official title: Efficacy of Preoperative Oral Iron Supplementation in Adolescents Undergoing Scoliosis Surgery

Funded at Columbia University Health Sciences · NIH-10912801 · Data updated 2026-11-12

This study is looking at how taking iron supplements before spinal fusion surgery can help teenagers with Adolescent Idiopathic Scoliosis feel better and recover faster, especially since many of them might be low on iron.

More Scoliosis research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$193,031
NIH project number5K23GM152933-02
Project IDNIH-10912801 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescent females scheduled for spinal fusion surgery due to Adolescent Idiopathic Scoliosis.

Less likely to help

Patients who are not undergoing scoliosis surgery or those who do not have iron deficiency may not benefit from this research.

What this research studies

This research investigates the effects of preoperative oral iron supplementation in adolescents who are scheduled for spinal fusion surgery due to Adolescent Idiopathic Scoliosis (AIS). The study aims to address the common issue of iron deficiency and anemia in this population, particularly among adolescent females who may experience additional iron loss during surgery. By monitoring iron levels and providing supplementation, the research seeks to optimize hemoglobin levels before surgery, potentially reducing the need for blood transfusions and improving overall surgical outcomes. Participants will be closely monitored to assess the impact of iron supplementation on their recovery and health.

Why it matters

Potential benefit: If successful, this research could lead to improved surgical outcomes and reduced complications for adolescents undergoing scoliosis surgery.

How similar studies have gone: Previous research has shown that preoperative iron supplementation can effectively improve hemoglobin levels and reduce transfusion rates in surgical patients, indicating a promising approach.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Eisler, Lisa Danielle — Columbia University Health Sciences
  • Study coordinator: Eisler, Lisa Danielle

Related research

Other NIH-funded projects on the same topics.

  • The RESILIENT Brace for teens with scoliosis

    A new flexible, adjustable scoliosis brace for adolescents to improve comfort, mobility, and real-time feedback to help keep curves from getting worse.

    NIH research Thinks Works, Pbc D/b/a Thinksworks · Austin, United States · NIH-11402856

  • Developmental mechanisms behind adolescent idiopathic scoliosis

    A program of researchers is studying why scoliosis appears in some children and aims to uncover genetic and developmental clues that could lead to better understanding and future treatments.

    NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11350943

  • Understanding why adolescent scoliosis develops and how to prevent it

    A research collaboration is studying why adolescent idiopathic scoliosis (AIS) happens and how it progresses, with the goal of finding ways to prevent and better treat it for affected children.

    NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11350942

  • Low oxygen and mitochondria's role in spine development and congenital scoliosis

    This research looks at how low oxygen and mitochondrial changes during pregnancy can disrupt early spine formation and lead to congenital scoliosis.

    NIH research University of Pennsylvania · Philadelphia, United States · NIH-11320814

  • Understanding genetic causes of scoliosis

    This work looks at whether genes called ADGRG6 and SOX9 and their cell signals help keep the spine straight and could lead to ways to prevent or reduce scoliosis, especially in adolescents.

    NIH research University of Texas at Austin · Austin, United States · NIH-11257280

  • Understanding the Causes of Adolescent Scoliosis

    This program aims to uncover the genetic and developmental reasons behind adolescent idiopathic scoliosis, a common spine condition in children.

    NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11121810

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.