Improving blood flow control after spinal cord injury using nerve stimulation and rehabilitation
Enhancing Sympathetic Outflow Control Following Spinal Cord Injury Using Targeted Plasticity Therapy
This study is looking at how using vagus nerve stimulation during rehab exercises can help people with cervical spinal cord injuries improve their movement and reduce muscle fatigue, making it easier for them to regain control and feel better overall.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11034111 on NIH RePORTER |
What this research studies
This research investigates how vagus nerve stimulation combined with rehabilitation can improve sympathetic outflow control in patients with cervical spinal cord injuries. By stimulating the vagus nerve during rehabilitation exercises, the study aims to enhance the brain's ability to reorganize and improve motor control systems. The researchers will evaluate the effectiveness of this approach in restoring blood flow and reducing muscle fatigue, which are common issues following such injuries. The study will also explore the best methods for delivering this stimulation to maximize patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced cervical spinal cord injuries and are facing challenges with blood flow control and muscle endurance.
Not a fit: Patients with spinal cord injuries at levels other than cervical or those with other complicating health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life for patients with cervical spinal cord injuries by enhancing their ability to control blood flow and reduce muscle fatigue.
How similar studies have performed: Previous research has shown promising results using nerve stimulation techniques for enhancing motor control and recovery in similar patient populations.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Ganzer, Patrick D — University of Miami School of Medicine
- Study coordinator: Ganzer, Patrick D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.