Improving blood compatibility of medical devices
Nanostructured Surfaces With Improved Hemocompatibility
['FUNDING_R21'] · GEORGE MASON UNIVERSITY · NIH-11074798
This study is working on making heart devices like stents and valves safer by creating new materials that help prevent blood clots, which can be a problem for patients using these implants.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGE MASON UNIVERSITY (nih funded) |
| Locations | 1 site (FAIRFAX, UNITED STATES) |
| Trial ID | NIH-11074798 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the safety and effectiveness of blood-contacting medical devices, such as stents and heart valves, by developing new biomaterials that reduce the risk of blood clot formation. The approach involves studying how blood interacts with these materials to prevent thrombosis, which is a significant complication in patients receiving these implants. By understanding the mechanisms of protein adsorption and platelet activation, the research aims to create surfaces that minimize adverse reactions when in contact with blood. This could lead to safer medical devices that improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who require blood-contacting medical devices, such as those undergoing stent or heart valve procedures.
Not a fit: Patients who do not require any form of blood-contacting medical devices may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of thrombosis and improve the longevity and effectiveness of implantable medical devices.
How similar studies have performed: Previous research has shown promise in developing biomaterials that enhance hemocompatibility, indicating that this approach has potential for success.
Where this research is happening
FAIRFAX, UNITED STATES
- GEORGE MASON UNIVERSITY — FAIRFAX, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: POPAT, KETUL CHANDRAKANT — GEORGE MASON UNIVERSITY
- Study coordinator: POPAT, KETUL CHANDRAKANT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.