Improving blood compatibility of medical devices
Official title: Nanostructured Surfaces With Improved Hemocompatibility
Funded at George Mason University · NIH-11074798 · Data updated 2026-11-12
This study is working on making heart devices like stents and valves safer by creating new materials that help prevent blood clots, which can be a problem for patients using these implants.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | George Mason University NIH-funded |
| Lab location | 1 site (Fairfax, United States) |
| Project start | August 18, 2022 |
| Project end | June 30, 2026 |
| Funding year | 2023 |
| Award (this year) | $195,487 |
| NIH project number | 7R21EB033511-03 |
| Project ID | NIH-11074798 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who require blood-contacting medical devices, such as those undergoing stent or heart valve procedures.
✕Less likely to help
Patients who do not require any form of blood-contacting medical devices may not benefit from this research.
What this research studies
This research focuses on enhancing the safety and effectiveness of blood-contacting medical devices, such as stents and heart valves, by developing new biomaterials that reduce the risk of blood clot formation. The approach involves studying how blood interacts with these materials to prevent thrombosis, which is a significant complication in patients receiving these implants. By understanding the mechanisms of protein adsorption and platelet activation, the research aims to create surfaces that minimize adverse reactions when in contact with blood. This could lead to safer medical devices that improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of thrombosis and improve the longevity and effectiveness of implantable medical devices.
How similar studies have gone: Previous research has shown promise in developing biomaterials that enhance hemocompatibility, indicating that this approach has potential for success.
Where this research is happening
-
George Mason University
Fairfax, United States Active
Researchers
- Principal investigator: Popat, Ketul Chandrakant — George Mason University
- Study coordinator: Popat, Ketul Chandrakant
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.