Improving bladder control after spinal cord injuries using electrical stimulation
Official title: Targeting urinary tract dysfunctions after spinal cord injury with epidural stimulation
Funded at University of Louisville · NIH-10920454 · Data updated 2026-11-12
This study is looking at how a special treatment using electrical stimulation on the spinal cord can help people with spinal cord injuries regain control over their bladder, and it also tests if combining this treatment with walking exercises can make it work even better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Louisville NIH-funded |
| Lab location | 1 site (Louisville, United States) |
| Project start | September 15, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $335,999 |
| NIH project number | 5R01DK133195-02 |
| Project ID | NIH-10920454 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced spinal cord injuries and are facing urinary tract dysfunctions.
✕Less likely to help
Patients with intact bladder function or those who do not have spinal cord injuries may not benefit from this research.
What this research studies
This research investigates the use of spinal cord epidural stimulation (scES) to restore bladder control in individuals with spinal cord injuries. By applying electrical fields directly to the spinal cord, the study aims to activate specific neural circuits that regulate bladder functions. The approach involves using a multi-electrode array to stimulate various structures simultaneously, potentially enhancing the effectiveness of bladder management. The research will also explore the combination of scES with locomotor training to optimize outcomes for patients.
Why it matters
Potential benefit: If successful, this research could significantly improve bladder control and quality of life for individuals with spinal cord injuries.
How similar studies have gone: Previous research has shown promise in using electrical stimulation for bladder control, indicating potential success for this approach.
Where this research is happening
-
University of Louisville
Louisville, United States Active
Researchers
- Principal investigator: Hubscher, Charles H. — University of Louisville
- Study coordinator: Hubscher, Charles H.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.