NIH-funded research NIH-funded research

Improving biomedical research with advanced electron paramagnetic resonance technology

Official title: Enhancing Biomedical Education and Research through the Acquisition of an Electron Paramagnetic Resonance Instrument

Funded at University of Puerto Rico Rio Piedras · NIH-10879634 · Data updated 2026-11-12

This study is looking to get a new, advanced machine that helps scientists at the University of Puerto Rico learn more about how certain substances in our bodies relate to diseases and treatments, which can lead to better health solutions for everyone, especially after recent challenges the community has faced.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Puerto Rico Rio Piedras
NIH-funded
Lab location1 site (San Juan, United States)
Project startAugust 1, 2024
Project endJuly 31, 2025
Funding year2024
Award (this year)$249,951
NIH project number1S10GM154262-01
Project IDNIH-10879634 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for benefiting from this research include individuals affected by diseases that involve biomolecular interactions and require innovative drug delivery solutions.

Less likely to help

Patients with conditions that do not involve paramagnetic species or biomolecular interactions may not receive direct benefits from this research.

What this research studies

This research aims to acquire a state-of-the-art Electron Paramagnetic Resonance (EPR) spectrometer to enhance biomedical research capabilities at the University of Puerto Rico. The EPR technology will allow researchers to study paramagnetic species in biological materials and living organisms, providing insights into disease progression, drug design, and biomolecular interactions. By linking paramagnetic spin labels to biomedically relevant agents, the research will enable a deeper understanding of various health conditions. This initiative is particularly important for rebuilding research efforts following recent natural disasters and economic challenges.

Why it matters

Potential benefit: If successful, this research could lead to significant advancements in understanding disease mechanisms and improving drug delivery systems for patients.

How similar studies have gone: Other research utilizing EPR technology has shown promising results in studying biomolecular interactions, indicating that this approach has a solid foundation in scientific literature.

Where this research is happening

  • University of Puerto Rico Rio Piedras
    San Juan, United States
    Active

Researchers

  • Principal investigator: Tinoco, Arthur David — University of Puerto Rico Rio Piedras
  • Study coordinator: Tinoco, Arthur David

Related research

Other NIH-funded projects on the same topics.

  • Understanding how non-coding changes affect heart development

    A study to figure out how non-coding genetic changes influence heart development in CHD, focusing on how they alter heart-related transcription factors and gene regulation.

    NIH research University of Puerto Rico Rio Piedras · San Juan, United States · NIH-11424549

  • Alcohol and sleep: how alcohol changes brain sleep circuits in fruit flies

    A small study in fruit flies looks at how alcohol changes sleep-circuit signals, with the goal of understanding sleep problems in people with alcohol use issues.

    NIH research University of Puerto Rico Rio Piedras · San Juan, United States · NIH-11424472

  • Basonuclin-1 and the progression of inflammatory breast cancer

    Researchers are studying how a gene called basonuclin-1 may drive aggressive, hard-to-treat inflammatory breast cancer to help find new ways to stop its spread.

    NIH research University of Puerto Rico Rio Piedras · San Juan, United States · NIH-11385472

  • Tiny brain sensor to detect neuropeptide Y (NPY) signals

    This project builds a very small, aptamer-coated sensor to continuously read neuropeptide Y (NPY) released by brain cells so researchers can link NPY signals to neurological problems.

    NIH research University of Puerto Rico Rio Piedras · San Juan, United States · NIH-11248769

  • Creating a new tool to measure NPY levels in the brain

    This study is working on a tiny device that can keep track of a brain chemical called Neuropeptide Y, which might help us understand its role in different brain disorders, making it easier to learn how it affects brain health.

    NIH research University of Puerto Rico Rio Piedras · San Juan, United States · NIH-11027487

  • Training underrepresented minority students in neuroscience at the University of Puerto Rico

    The NeuroGRAD@UPR program is designed to help underrepresented minority students succeed in neuroscience by offering training, mentorship, and hands-on experiences, so they can build their skills and confidence for a bright future in the field.

    NIH research University of Puerto Rico Rio Piedras · San Juan, United States · NIH-10897174

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.