Improving awareness of low blood sugar in people with type 1 diabetes

Restoring awareness of hypoglycemia in type 1 diabetes

NIH-funded research University of Pennsylvania · NIH-11076662

This study is looking for ways to help people with type 1 diabetes recognize when their blood sugar is low, using different methods like education and new treatments, to keep them safe and healthy over two years.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11076662 on NIH RePORTER

What this research studies

This research investigates how to restore awareness of low blood sugar (hypoglycemia) in individuals with type 1 diabetes. It involves a 24-month clinical trial that uses various interventions, including education on avoiding hypoglycemia, advanced insulin delivery systems, and new glucagon treatments. The goal is to understand the factors that affect the body's response to low blood sugar and to improve safety and glycemic control for patients. Participants will be monitored closely to assess the effectiveness of these approaches.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have type 1 diabetes and experience impaired awareness of hypoglycemia.

Not a fit: Patients who do not have type 1 diabetes or those who do not experience issues with hypoglycemia awareness may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could help individuals with type 1 diabetes better manage their blood sugar levels and reduce the risk of severe hypoglycemia.

How similar studies have performed: Previous research has shown promise in using educational and technological interventions to improve hypoglycemia awareness, making this approach both relevant and potentially impactful.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Brittle Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.