Improving asthma control in overweight adults with late-onset asthma using L-citrulline
SANDIA: Supplementing L-citrulline to overweight late Asthma oNset phenotypes to increase airway L-arginine/ADMA ratio and Improve Asthma control
['FUNDING_R01'] · UNIVERSITY OF COLORADO DENVER · NIH-10692823
This study is looking at how taking L-citrulline might help overweight adults who developed asthma later in life by improving their breathing and reducing asthma symptoms.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-10692823 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of supplementing L-citrulline in overweight adults who developed asthma later in life. The study focuses on understanding how this supplementation can improve the balance of L-arginine and asymmetric dimethylarginine (ADMA) in the body, which is crucial for better airway function. By addressing the unique inflammatory responses in this group, the research aims to enhance asthma control and overall respiratory health. Participants will be monitored for changes in their asthma symptoms and lung function as part of the study.
Who could benefit from this research
Good fit: Ideal candidates for this research are overweight adults who have developed asthma after childhood and experience poorly controlled symptoms.
Not a fit: Patients who do not have late-onset asthma or are not overweight may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved asthma management and quality of life for overweight adults with late-onset asthma.
How similar studies have performed: Previous research has shown promising results in using similar approaches to improve asthma control in specific patient populations, indicating potential for success in this study.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HOLGUIN, FERNANDO — UNIVERSITY OF COLORADO DENVER
- Study coordinator: HOLGUIN, FERNANDO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.