Improving artificial lung systems to better meet patient needs

Automated control of artificial lung systems to meet patient metabolic needs

NIH-funded research Veterans Health Administration · NIH-11229633

This study is working on a smart artificial lung that can change how it works based on what each patient with severe lung disease needs, helping them feel more comfortable and active, and it will be tested on animals before it can be used in people who can't get a lung transplant.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVeterans Health Administration NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11229633 on NIH RePORTER

What this research studies

This research focuses on developing advanced artificial lung systems that can automatically adjust to meet the changing respiratory and metabolic needs of patients with end-stage lung disease. By creating a control system that regulates carbon dioxide removal based on individual patient requirements, the project aims to enhance patient comfort and activity levels. The research involves testing these systems in animal models to ensure their effectiveness before potential application in human patients. Ultimately, the goal is to improve rehabilitation outcomes for patients who cannot receive lung transplants.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from end-stage lung disease who are not eligible for lung transplantation.

Not a fit: Patients with mild respiratory conditions or those who are candidates for lung transplantation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly enhance the quality of life and rehabilitation outcomes for patients with severe lung disease.

How similar studies have performed: Previous research has shown promise in developing artificial lung technologies, but this specific automated control approach is relatively novel.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.