Improving arm recovery after spinal cord injury
Enhancing Forelimb Recovery by Promoting Forelimb Corticospinal Tract Regeneration after Spinal Cord Injury
This study is looking for ways to help people with spinal cord injuries, especially those with quadriplegia, regain movement in their arms by figuring out how to make nerve pathways grow back better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA San Diego Healthcare System NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project ID | NIH-10977051 on NIH RePORTER |
What this research studies
This research investigates ways to enhance the regeneration of nerve pathways that control arm movement after spinal cord injuries. By using advanced techniques like RNA sequencing, the study aims to understand why nerve fibers for the arms do not regenerate as effectively as those for the legs. The researchers will explore experimental methods to promote the growth of these nerve fibers, potentially leading to better recovery of arm function. This work is particularly focused on patients with quadriplegia who have lost the ability to use their arms due to spinal cord injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced spinal cord injuries resulting in loss of arm function.
Not a fit: Patients with spinal cord injuries that do not affect arm function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved arm function and greater independence for patients with spinal cord injuries.
How similar studies have performed: Previous research has shown promise in enhancing nerve regeneration in spinal cord injuries, but this specific approach targeting forelimb recovery is relatively novel.
Where this research is happening
San Diego, United States
- VA San Diego Healthcare System — San Diego, United States (Active)
Researchers
- Principal investigator: Lu, Pengzhe — VA San Diego Healthcare System
- Study coordinator: Lu, Pengzhe
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.