NIH-funded research R01 grant

Improving antibiotic use when patients leave the hospital

Official title: Reducing Overuse of Antibiotics at Discharge: The ROAD Home Trial

Funded at University of Utah · NIH-10907571 · Data updated 2026-11-12

The ROAD Home study is looking at how to make sure patients get the right antibiotics when they leave the hospital, so they stay safe and healthy without getting too many unnecessary medications.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Utah
NIH-funded
Lab location1 site (Salt Lake City, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$500,000
NIH project number5R01HS029482-02
Project IDNIH-10907571 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients who are being discharged from hospitals and are prescribed antibiotics.

Less likely to help

Patients who are not prescribed antibiotics at discharge or those who are not transitioning from hospital care may not benefit from this research.

What this research studies

The ROAD Home trial aims to reduce the overprescription of antibiotics when patients are discharged from hospitals. This research involves 40 hospitals and focuses on implementing effective strategies to ensure that patients receive appropriate antibiotic prescriptions tailored to their specific needs. By evaluating the ROAD Home intervention, the study seeks to understand how to better manage antibiotic use during the critical transition from hospital to home. The goal is to enhance patient safety and reduce the risks associated with antibiotic overuse.

Why it matters

Potential benefit: If successful, this research could lead to safer antibiotic prescribing practices at discharge, reducing the risk of antibiotic resistance and improving patient outcomes.

How similar studies have gone: Previous research has shown that targeted antibiotic stewardship strategies can effectively reduce overprescribing, indicating that this approach has potential for success.

Where this research is happening

  • University of Utah
    Salt Lake City, United States
    Active

Researchers

  • Principal investigator: Vaughn, Valerie Michele — University of Utah
  • Study coordinator: Vaughn, Valerie Michele

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.