Improving antibiotic use to prevent surgical site infections
Official title: Targeting Surgical Site Infections through a Perioperative Antibiotic Clinical Decision Support Tool
Funded at Massachusetts General Hospital · NIH-10886594 · Data updated 2026-11-12
This study is working on a helpful tool for surgeons to make sure patients get the right antibiotics during surgery, which can help prevent infections and improve recovery for everyone, especially in unexpected surgery situations.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 30, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $465,144 |
| NIH project number | 5R01HS029172-03 |
| Project ID | NIH-10886594 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients undergoing surgical procedures who are at risk for surgical site infections.
✕Less likely to help
Patients who are not undergoing surgery or those who do not require antibiotic prophylaxis may not benefit from this research.
What this research studies
This research focuses on reducing the incidence of surgical site infections (SSIs) by developing a clinical decision support tool for perioperative antibiotic administration. It aims to enhance adherence to the more comprehensive guidelines set by the Infectious Disease Society of America (IDSA), which include specific antibiotic selection, weight-adjusted dosing, and timely re-dosing during surgeries. By analyzing data from surgical cases, the project seeks to identify and address gaps in current practices, especially in unplanned surgical scenarios. The goal is to provide surgeons with better tools to make informed decisions about antibiotic use, ultimately improving patient outcomes.
Why it matters
Potential benefit: If successful, this research could significantly reduce the rates of surgical site infections, leading to better patient outcomes and lower healthcare costs.
How similar studies have gone: Previous research has shown that improved adherence to comprehensive antibiotic guidelines can lead to reduced infection rates, indicating potential success for this approach.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Bardia, Amit — Massachusetts General Hospital
- Study coordinator: Bardia, Amit
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.