Improving antibiotic use in dialysis centers

Optimizing Antimicrobial Use in Maintenance Dialysis Units (OPTIMUS)

NIH-funded research Miriam Hospital · NIH-10877742

This study is looking at ways to help doctors use antibiotics more wisely for patients on dialysis, so they can stay safe and healthy by reducing the risk of infections caused by tough germs.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMiriam Hospital NIH-funded
Lab location1 site (Providence, United States)
Project IDNIH-10877742 on NIH RePORTER

What this research studies

This research focuses on reducing the inappropriate use of antibiotics in maintenance hemodialysis units, where patients are at high risk for multidrug-resistant organisms (MDRO). The study aims to implement antimicrobial stewardship programs that educate healthcare providers and improve prescribing practices. By analyzing data and outcomes from previous programs, the research seeks to identify and address barriers to effective antibiotic prescribing. Ultimately, the goal is to enhance patient safety and reduce infection rates among dialysis patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients receiving maintenance hemodialysis who may be at risk for infections due to antibiotic misuse.

Not a fit: Patients who are not undergoing maintenance hemodialysis or those who do not require antibiotic treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly lower the rates of infections and improve overall health outcomes for patients undergoing maintenance hemodialysis.

How similar studies have performed: Previous studies have shown success in reducing antibiotic use and infection rates through antimicrobial stewardship programs in similar healthcare settings.

Where this research is happening

Providence, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.