Improving antibiotic use in breastfeeding mothers and their infants
Optimization of Antibiotics in Mothers and their Breastfed Infants Using Pharmacomicrobiomic and Metabolomic Analyses
This study is looking at how antibiotics that breastfeeding moms take can affect their babies through breast milk, helping us learn more about how to keep both moms and their little ones healthy during treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11143430 on NIH RePORTER |
What this research studies
This research focuses on understanding how antibiotics taken by breastfeeding mothers affect their infants through breast milk. It investigates the pharmacokinetics of antibiotic transfer, the impact on the infant's microbiome and immune function, and the role of breast milk in supporting infant health during antibiotic treatment. The study employs advanced techniques in pharmacomicrobiomics and metabolomics to analyze these interactions and aims to optimize antibiotic therapy for better maternal and infant health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include breastfeeding mothers who require antibiotic treatment and their infants aged 0-11 years.
Not a fit: Patients who are not breastfeeding or whose infants are older than 11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer antibiotic use in breastfeeding mothers, minimizing risks to their infants while ensuring effective treatment.
How similar studies have performed: Previous research has shown promising results in understanding the effects of maternal antibiotics on infants, but this study aims to explore these interactions in greater depth using novel methodologies.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Tremoulet, Adriana H — University of California, San Diego
- Study coordinator: Tremoulet, Adriana H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.