Improving antibiotic use in breastfeeding mothers and their infants
Optimization of Antibiotics in Mothers and their Breastfed Infants Using Pharmacomicrobiomic and Metabolomic Analyses
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-10907648
This study looks at how antibiotics that breastfeeding moms take can affect their babies through breast milk, helping us understand how these medicines interact with the baby's health and gut bacteria, so we can make sure moms get the right treatment while keeping their little ones healthy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10907648 on ClinicalTrials.gov |
What this research studies
This research investigates how antibiotics taken by breastfeeding mothers affect their infants through breast milk. It focuses on understanding the pharmacokinetics of antibiotic transfer, the impact on the infant's microbiome and immune system, and the role of breast milk in supporting infant health. The study employs advanced techniques in pharmacomicrobiomics and metabolomics to analyze these effects. By integrating clinical, basic science, and data science approaches, the research aims to optimize antibiotic treatment for mothers while ensuring the health of their breastfed infants.
Who could benefit from this research
Good fit: Ideal candidates for this research include breastfeeding mothers who are undergoing antibiotic treatment and their infants.
Not a fit: Patients who are not breastfeeding or those whose infants are older than 11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer antibiotic use in breastfeeding mothers, minimizing potential negative effects on their infants.
How similar studies have performed: Previous research has shown promising results in understanding the effects of maternal antibiotics on infants, but this specific approach is innovative and aims to fill existing knowledge gaps.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TREMOULET, ADRIANA H — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: TREMOULET, ADRIANA H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.