Improving Antibiotic Use for Breastfeeding Mothers and Their Babies
Optimization of Antibiotics in Mothers and their Breastfed Infants Using Pharmacomicrobiomic and Metabolomic Analyses (mPRINT P50)
This project aims to find the best ways to use antibiotics in mothers who are breastfeeding and their infants.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11143908 on NIH RePORTER |
What this research studies
We want to understand how antibiotics affect both mothers and their breastfed babies. This involves looking closely at breast milk, the baby's gut bacteria (microbiome), and how the body processes medicines (metabolomics). Our goal is to make sure antibiotics are as effective and safe as possible for this special population. By gathering this information, we hope to provide better guidance for doctors and parents.
Who could benefit from this research
Good fit: Mothers who are breastfeeding and require antibiotic treatment, along with their infants, would be the focus of the research supported by this center.
Not a fit: Patients who are not breastfeeding or are not infants would not directly benefit from the specific findings of this research.
Why it matters
Potential benefit: This work could lead to safer and more effective antibiotic treatments for breastfeeding mothers and their infants, reducing potential side effects and improving health outcomes.
How similar studies have performed: While the overall approach of optimizing drug use is established, this specific focus on pharmacomicrobiomics and metabolomics in breastfeeding mothers and infants represents a novel and comprehensive approach.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Tremoulet, Adriana H — University of California, San Diego
- Study coordinator: Tremoulet, Adriana H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.