Improving Antibiotic Prescriptions for Patients Leaving the Hospital

Leveraging inpatient antimicrobial stewardship infrastructure to improve antimicrobial-prescribing at hospital discharge

NIH-funded research Iowa City VA Medical Center · NIH-11142381

This project aims to help hospitals ensure patients receive the most appropriate antibiotics when they go home, reducing risks like C. difficile infections and antibiotic resistance.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIowa City VA Medical Center NIH-funded
Lab location1 site (Iowa City, United States)
Project IDNIH-11142381 on NIH RePORTER

What this research studies

Antibiotic overuse is a major concern, contributing to antibiotic resistance and harmful side effects like C. difficile infections. While hospitals have programs to manage antibiotic use during a stay, a significant portion of antibiotic exposure happens after patients leave. This project will look at how current hospital antibiotic management can be extended to improve prescriptions given at discharge. By understanding why some post-discharge antibiotic prescriptions might be unnecessary or suboptimal, we can develop better strategies to protect patients. Our goal is to make sure you receive the safest and most effective antibiotic treatment when you return home.

Who could benefit from this research

Good fit: Patients who receive antibiotics during a hospital stay and are prescribed antibiotics to take home are the focus of this research.

Not a fit: Patients who do not receive antibiotics during or after a hospital stay would not directly benefit from this specific improvement in prescribing practices.

Why it matters

Potential benefit: If successful, this work could lead to fewer serious infections like C. difficile and help slow the development of antibiotic-resistant germs, improving patient safety.

How similar studies have performed: While inpatient antibiotic stewardship programs have shown success, improving post-discharge prescribing is a newer area with critical gaps in current understanding.

Where this research is happening

Iowa City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.