NIH-funded research R01 grant

Improving ankle push-off and walking in children with cerebral palsy

Official title: Augmenting Ankle Plantarflexor Function and Walking Capacity in Children with Cerebral Palsy

Funded at Northern Arizona University · NIH-11161507 · Data updated 2026-11-12

A lightweight wearable ankle robot that can either give resistance to build strength or provide assistance to make walking easier is being used to help children with cerebral palsy walk better.

More Cerebral Palsy research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthern Arizona University
NIH-funded
Lab location1 site (Flagstaff, United States)
Project startSeptember 22, 2021
Project endAugust 31, 2026
Funding year2025
Award (this year)$412,402
NIH project number5R01HD107277-05
Project IDNIH-11161507 on NIH RePORTER

Who could benefit from this research

Could help

Children with cerebral palsy who have difficulty with ankle push-off, abnormal gait patterns, and the ability to participate in supervised walking training are the ideal candidates.

Less likely to help

Children whose walking limitations are caused primarily by non-ankle issues (for example severe hip/knee instability or medical conditions preventing safe participation) may not benefit from this ankle-focused device.

What this research studies

Your child would wear a lightweight, dual-mode ankle device that can switch between providing targeted resistance to train muscles and giving adaptive assistance during harder or longer walks. Therapists will use resistance during focused walking sessions to encourage stronger, more efficient ankle muscle use, and will use assistance when sustained or high-intensity walking is needed. The team will measure changes in ankle muscle function, walking speed, endurance, and everyday activity levels before and after the training. Visits and testing would occur at the research site and include follow-up checks to track lasting changes.

Why it matters

Potential benefit: If successful, this approach could help children with cerebral palsy walk more efficiently, farther, and with less effort.

How similar studies have gone: Robotic ankle assistance and targeted resistance therapies have shown promise separately for improving gait in cerebral palsy, but combining adaptive assistance and resistance in a single wearable device is relatively new.

Where this research is happening

  • Northern Arizona University
    Flagstaff, United States
    Active

Researchers

  • Principal investigator: Lerner, Zachary Forest — Northern Arizona University
  • Study coordinator: Lerner, Zachary Forest

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.