Improving animal models for gene and regenerative therapies
Official title: Enhancing Rigor and Reproducibility of Translational Nonhuman Primate Models for Genetic and Regenerative Therapies
Funded at University of California at Davis · NIH-10858290 · Data updated 2026-11-12
This study is working to make it easier to understand how new gene and regenerative therapies might work by using advanced imaging techniques in nonhuman primates, which could lead to better and safer treatments for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $781,525 |
| NIH project number | 1R01OD036239-01 |
| Project ID | NIH-10858290 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that could benefit from genetic or regenerative therapies, particularly those involving immune system responses.
✕Less likely to help
Patients who do not have conditions related to genetic or regenerative therapies may not receive any benefit from this research.
What this research studies
This research aims to enhance the reliability and applicability of nonhuman primate models used in genetic and regenerative therapies. By integrating advanced imaging technologies and immunologic assessments, the project seeks to improve how these models are studied, particularly in monitoring gene transfer and immune responses. Patients may benefit from more effective therapies developed through these improved models, as they will provide better insights into treatment effects and safety. The research will focus on using total-body PET imaging and T-cell tracking to gather critical data that can translate into clinical applications.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer genetic and regenerative therapies for patients.
How similar studies have gone: Previous research has shown success in enhancing animal models for therapeutic applications, indicating that this approach has potential for meaningful advancements.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Tarantal, Alice F — University of California at Davis
- Study coordinator: Tarantal, Alice F
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.