Improving anesthesia to protect older adults from cognitive decline after surgery

Optimizing anesthesia to prevent postoperative cognitive and functional decline in older adults

NIH-funded research Oregon Health & Science University · NIH-11135546

This study is looking at how different kinds of anesthesia might help older adults recover better after surgery, especially by reducing confusion and memory problems afterward.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOregon Health & Science University NIH-funded
Lab location1 site (Portland, United States)
Project IDNIH-11135546 on NIH RePORTER

What this research studies

This research investigates how different types of anesthesia can affect the cognitive and functional recovery of older adults after surgery. It compares the use of inhalational agents to intravenous agents to determine which method may reduce the risk of postoperative delirium and cognitive dysfunction. By focusing on older surgical patients, the study aims to address a significant public health issue, as many older Americans undergo surgery. The research will involve clinical trials and the integration of geriatric medicine principles to enhance patient outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults who are scheduled to undergo surgical procedures.

Not a fit: Patients who are not undergoing surgery or are younger than the typical age range for this study may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved anesthesia practices that minimize cognitive decline and enhance recovery for older adults after surgery.

How similar studies have performed: Previous research has indicated that different anesthesia techniques can impact postoperative outcomes, suggesting that this approach may yield valuable insights.

Where this research is happening

Portland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions age associated diseaseage associated disorderage dependent diseaseage dependent disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.