Improving anesthesia techniques to prevent lung problems after abdominal surgery.

2/2: An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study.

NIH-funded research Massachusetts General Hospital · NIH-10586096

This study is looking at ways to help patients recover better after abdominal surgery by using special techniques during anesthesia to protect their lungs and reduce the chances of breathing problems afterward.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10586096 on NIH RePORTER

What this research studies

This research focuses on reducing postoperative pulmonary complications (PPCs) that can occur after abdominal surgery, which significantly affect recovery and can lead to serious health issues. The study investigates the role of specific anesthesia-related interventions, such as ventilatory strategies and the management of neuromuscular blocking agents, to enhance lung protection during surgery. By implementing these strategies, the research aims to improve patient outcomes and reduce the incidence of PPCs, which are currently a major cause of morbidity and mortality in surgical patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients scheduled for abdominal surgery who are at risk of developing postoperative pulmonary complications.

Not a fit: Patients who are not undergoing abdominal surgery or those with pre-existing severe lung conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer surgical procedures and improved recovery for patients undergoing abdominal surgery.

How similar studies have performed: Previous research has shown promising results in using anesthesia-centered strategies to reduce complications in surgical patients, indicating that this approach has potential for success.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.