Improving analysis of microbiome data to uncover hidden issues
Statistical methods for analyzing messy microbiome data: detection of hidden artifacts and robust modeling approaches
['FUNDING_R01'] · JOHNS HOPKINS UNIVERSITY · NIH-10914026
This study is working on new ways to better understand the tiny organisms in our bodies, called the microbiome, to help us learn how they affect our health, so patients can get clearer information about their own health conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10914026 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the analysis of microbiome data, which is crucial for understanding its impact on various health conditions. It aims to develop advanced statistical methods that can detect hidden artifacts and biases in microbiome sequencing data, ensuring more accurate results. By addressing challenges such as experimental bias and data sparsity, the project seeks to improve the reliability of microbiome studies. Patients may benefit from more precise insights into how their microbiome affects their health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions influenced by microbiome health, such as gastrointestinal disorders or metabolic diseases.
Not a fit: Patients without microbiome-related health issues or those not participating in microbiome studies may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of microbiome-related health issues, ultimately improving patient care and treatment options.
How similar studies have performed: Previous research has shown that improving statistical methods for microbiome data analysis can lead to significant advancements in understanding health impacts, indicating a promising direction for this project.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHAO, NI — JOHNS HOPKINS UNIVERSITY
- Study coordinator: ZHAO, NI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.