Improving analysis of circular RNAs for disease research
Official title: Enabling comprehensive and user-friendly circular RNA analyses with circtools.cloud
Funded at University of Arizona · NIH-10881580 · Data updated 2026-11-12
This study is working on creating easy-to-use software that helps scientists find and understand circular RNAs, which are important for studying diseases like cancer and heart problems, so more researchers can join in on this important work without needing special computer skills.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | September 18, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $660,671 |
| NIH project number | 1R01HG013124-01A1 |
| Project ID | NIH-10881580 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions related to cancer, neurological disorders, or cardiovascular diseases.
✕Less likely to help
Patients with diseases not associated with circular RNAs or those who do not have access to the necessary sequencing technology may not benefit from this research.
What this research studies
This research focuses on enhancing the analysis of circular RNAs (circRNAs), which are important biomarkers for various diseases including cancer and cardiovascular conditions. The project aims to develop user-friendly software tools that simplify the detection and analysis of circRNAs from raw sequencing data, making it accessible to researchers without extensive bioinformatics expertise. By addressing the computational challenges and infrastructure needs, this research seeks to empower more scientists to contribute to the understanding of circRNAs and their roles in human health.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for diseases associated with circular RNAs.
How similar studies have gone: Previous research has shown promise in the analysis of circular RNAs, but this approach aims to significantly enhance accessibility and usability, making it a novel contribution to the field.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Jakobi, Tobias — University of Arizona
- Study coordinator: Jakobi, Tobias
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.