Improving analysis of brain connectivity in Alzheimer's disease
Official title: Statistical Methods for Whole-Brain Dynamic Connectivity Analysis
Funded at Wake Forest University Health Sciences · NIH-11061350 · Data updated 2026-11-12
This study is looking at how different parts of the brain work together, especially in people with Alzheimer's disease, to help researchers and doctors find better ways to understand and treat brain disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project start | March 1, 2023 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $144,490 |
| NIH project number | 5K25EB032903-03 |
| Project ID | NIH-11061350 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or those experiencing cognitive decline.
✕Less likely to help
Patients with brain disorders unrelated to Alzheimer's disease may not benefit directly from this research.
What this research studies
This research focuses on developing new statistical methods to analyze how different parts of the brain connect and communicate, particularly in conditions like Alzheimer's disease. By using advanced techniques to study brain scans, the research aims to identify changes in brain connectivity that occur over time, which could lead to better understanding and treatment of brain disorders. The goal is to create tools that can help researchers and clinicians assess brain function more accurately and identify potential biomarkers for early intervention.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for patients with Alzheimer's disease and other brain disorders.
How similar studies have gone: Previous research has shown promise in using dynamic connectivity analysis for understanding brain disorders, but this approach aims to unify and enhance existing methods.
Where this research is happening
-
Wake Forest University Health Sciences
Winston-Salem, United States Active
Researchers
- Principal investigator: Shappell, Heather Marie — Wake Forest University Health Sciences
- Study coordinator: Shappell, Heather Marie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.