Improving analysis of brain connectivity in Alzheimer's disease
Statistical Methods for Whole-Brain Dynamic Connectivity Analysis
['FUNDING_OTHER'] · WAKE FOREST UNIVERSITY HEALTH SCIENCES · NIH-11061350
This study is looking at how different parts of the brain work together, especially in people with Alzheimer's disease, to help researchers and doctors find better ways to understand and treat brain disorders.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WAKE FOREST UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (WINSTON-SALEM, UNITED STATES) |
| Trial ID | NIH-11061350 on ClinicalTrials.gov |
What this research studies
This research focuses on developing new statistical methods to analyze how different parts of the brain connect and communicate, particularly in conditions like Alzheimer's disease. By using advanced techniques to study brain scans, the research aims to identify changes in brain connectivity that occur over time, which could lead to better understanding and treatment of brain disorders. The goal is to create tools that can help researchers and clinicians assess brain function more accurately and identify potential biomarkers for early intervention.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or those experiencing cognitive decline.
Not a fit: Patients with brain disorders unrelated to Alzheimer's disease may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for patients with Alzheimer's disease and other brain disorders.
How similar studies have performed: Previous research has shown promise in using dynamic connectivity analysis for understanding brain disorders, but this approach aims to unify and enhance existing methods.
Where this research is happening
WINSTON-SALEM, UNITED STATES
- WAKE FOREST UNIVERSITY HEALTH SCIENCES — WINSTON-SALEM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHAPPELL, HEATHER MARIE — WAKE FOREST UNIVERSITY HEALTH SCIENCES
- Study coordinator: SHAPPELL, HEATHER MARIE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease