Improving Alzheimer's Disease Treatment Development with Computer Simulations
ACTS (AD Clinical Trial Simulation): Developing Advanced Informatics Approaches for an Alzheimer's Disease Clinical Trial Simulation System
This project is building a computer system to help design better clinical trials for Alzheimer's disease using information from real patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Jacksonville NIH-funded |
| Lab location | 1 site (Jacksonville, United States) |
| Project ID | NIH-11191533 on NIH RePORTER |
What this research studies
Alzheimer's disease causes severe memory loss and affects millions, yet effective treatments are still needed. Traditional clinical trials are expensive and take a long time, and their results might not always apply to everyone in real life. Our goal is to create a powerful computer simulation system that uses real patient health information to test different trial designs. This will help researchers make smarter decisions about how to run future studies, potentially speeding up the discovery of new treatments.
Who could benefit from this research
Good fit: This project does not directly involve patient participation, but its ultimate goal is to benefit individuals living with Alzheimer's disease and related dementias.
Not a fit: Patients not affected by Alzheimer's disease or related dementias would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this system could help researchers design more efficient and effective clinical trials, leading to faster development of new treatments for Alzheimer's disease.
How similar studies have performed: Clinical trial simulation is an increasingly recognized approach for refining study protocols, and this project aims to advance its application specifically for Alzheimer's disease using real-world data.
Where this research is happening
Jacksonville, United States
- Mayo Clinic Jacksonville — Jacksonville, United States (Active)
Researchers
- Principal investigator: Tao, Cui — Mayo Clinic Jacksonville
- Study coordinator: Tao, Cui
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.