NIH-funded research R01 grant

Improving alcohol treatment engagement for patients with liver disease

Official title: Adaptive Interventions to Improve Alcohol Treatment Engagement among Alcohol-related Liver Disease Patients

Funded at University of Michigan at Ann Arbor · NIH-10875382 · Data updated 2026-11-12

This study is looking to help people with alcohol-related liver disease get more involved in their treatment by using a mobile app and personalized support, making it easier for them to stay on track and improve their health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startJuly 1, 2023
Project endJune 30, 2028
Funding year2024
Award (this year)$645,878
NIH project number5R01AA030748-02
Project IDNIH-10875382 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who have been diagnosed with alcohol-related liver disease and have not engaged in treatment in the past month.

Less likely to help

Patients who are not diagnosed with alcohol-related liver disease or who have recently engaged in alcohol treatment may not benefit from this research.

What this research studies

This research aims to enhance the engagement of patients with alcohol-related liver disease (ALD) in treatment programs. It employs an adaptive intervention strategy that tailors support based on individual patient responses, using a mobile app and additional resources to encourage participation in alcohol treatment. The study will involve patients from hepatology clinics who have been diagnosed with ALD and have not engaged in treatment recently. By identifying those who may need extra help, the research seeks to improve both alcohol consumption and liver health outcomes.

Why it matters

Potential benefit: If successful, this research could significantly increase the number of ALD patients receiving effective treatment, leading to better health outcomes and reduced mortality.

How similar studies have gone: Previous research has shown that adaptive interventions can effectively improve treatment engagement in various health conditions, suggesting potential success for this approach in ALD.

Where this research is happening

  • University of Michigan at Ann Arbor
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Mellinger, Jessica Leigh — University of Michigan at Ann Arbor
  • Study coordinator: Mellinger, Jessica Leigh

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.