Improving aerobic exercise response in breast cancer survivors
Official title: A Randomized Trial to Minimize Non-Response to Aerobic Training in Operable Breast Cancer
Funded at Sloan-Kettering Inst Can Research · NIH-10976874 · Data updated 2026-11-12
This study is looking at how to make aerobic exercise more effective for women who have finished treatment for early breast cancer, by testing if longer and more intense workouts can help improve heart and lung fitness, which is important for staying healthy.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | April 1, 2025 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $649,419 |
| NIH project number | 4R37CA248665-06 |
| Project ID | NIH-10976874 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women who have been diagnosed with early breast cancer and are currently undergoing or have completed treatment.
✕Less likely to help
Patients who are not breast cancer survivors or those with contraindications to aerobic exercise may not benefit from this research.
What this research studies
This research investigates how to enhance the effectiveness of aerobic exercise therapy for women who have undergone treatment for early breast cancer. The study aims to determine if increasing the duration and intensity of aerobic training can lead to better improvements in cardiorespiratory fitness, which is crucial for reducing the risk of cardiovascular disease. Participants will engage in a structured aerobic exercise program, and their fitness responses will be closely monitored to identify factors that influence success. The research also seeks to understand the long-term benefits of aerobic training and the barriers that may prevent some patients from achieving optimal fitness levels.
Why it matters
Potential benefit: If successful, this research could significantly improve the health outcomes and quality of life for breast cancer survivors by reducing their risk of cardiovascular disease.
How similar studies have gone: Previous research has shown that aerobic exercise can improve fitness in cancer survivors, but this specific approach to increasing exercise volume and duration is novel.
Where this research is happening
-
Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Scott, Jessica — Sloan-Kettering Inst Can Research
- Study coordinator: Scott, Jessica
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.