Improving adherence to hormone therapy for breast cancer patients

Optimizing Endocrine Therapy Adherence through Motivational Interviewing and Text Interventions

NIH-funded research Univ of North Carolina Chapel Hill · NIH-10686270

This study is looking for ways to help women with hormone receptor-positive breast cancer, especially younger and Black women, stick to their prescribed hormone therapy by using friendly conversations and text messages to make taking their medication easier and more consistent over five years.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-10686270 on NIH RePORTER

What this research studies

This research focuses on enhancing adherence to endocrine therapy (ET) for patients with hormone receptor-positive breast cancer. It employs motivational interviewing and text message interventions to encourage patients to consistently take their prescribed medication over a five-year period. By addressing barriers to adherence, the study aims to improve patient outcomes and reduce disparities in treatment effectiveness, particularly among younger and Black women. The approach is designed to be accessible and applicable to diverse patient populations.

Who could benefit from this research

Good fit: Ideal candidates for this research are women diagnosed with hormone receptor-positive breast cancer who are starting or currently on endocrine therapy.

Not a fit: Patients with non-hormone receptor-positive breast cancer or those who are not prescribed endocrine therapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve survival rates and quality of life for breast cancer patients by ensuring they adhere to life-saving medication.

How similar studies have performed: Previous research has shown promise in using behavioral interventions to improve medication adherence, indicating that this approach could be effective.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast CancerCancersneoplasm/cancerDiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.