Improving adherence to HIV treatment using a urine test.

Randomized Trial to Optimize Virologic Suppression Rates Using a Point-of-Care Urine Monitoring Assay (ROVING-PUMA)

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11036326

This study is testing a new urine test that helps people with HIV see if they're taking their medication as they should, making it easier for them to stick to their treatment and stay healthy.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded)
Locations1 site (SAN FRANCISCO, UNITED STATES)
Trial IDNIH-11036326 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing the effectiveness of HIV treatment by developing a point-of-care urine test that measures adherence to antiretroviral therapy (ART). By using a new immunoassay to detect drug levels in urine, the study aims to provide real-time feedback to patients about their medication adherence. This approach is designed to address the common challenge of patients not taking their medication as prescribed, which can lead to lower rates of virologic suppression. The research will involve participants who are currently on ART and will assess how this testing method can improve their treatment outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 21 and older who are currently receiving antiretroviral therapy for HIV.

Not a fit: Patients who are not currently on antiretroviral therapy or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved adherence to HIV treatment, resulting in better health outcomes for patients.

How similar studies have performed: Previous research has shown that real-time monitoring of medication adherence can significantly improve patient outcomes, suggesting that this approach may be effective.

Where this research is happening

SAN FRANCISCO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.