Improving access to treatments for ALS patients
Official title: Access for All in ALS (ALL ALS) West Clinical Coordinating Center
Funded at St. Joseph's Hospital and Medical Center · NIH-11185475 · Data updated 2026-11-12
This study is working to improve new treatments for ALS by gathering important health information and samples from both patients with symptoms and those without, so we can better understand the disease and help more people across the country.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | St. Joseph's Hospital and Medical Center NIH-funded |
| Lab location | 1 site (Phoenix, United States) |
| Project start | September 25, 2023 |
| Project end | September 24, 2025 |
| Funding year | 2024 |
| Award (this year) | $14,234,367 |
| NIH project number | 3OT2NS136939-01S1 |
| Project ID | NIH-11185475 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include individuals diagnosed with ALS, as well as asymptomatic mutation carriers of the disease.
✕Less likely to help
Patients with other neurodegenerative diseases or those not diagnosed with ALS may not receive any benefit from this research.
What this research studies
This research focuses on enhancing the development of new therapies for amyotrophic lateral sclerosis (ALS) by creating a comprehensive clinical research coordinating center. It aims to collect and analyze high-quality biosamples and clinical data from ALS patients, including both symptomatic and asymptomatic individuals. The project will utilize a public-private partnership to accelerate the regulatory science needed for effective drug development, while also expanding existing studies to include diverse patient populations across the country.
Why it matters
Potential benefit: If successful, this research could lead to the development of new treatments that significantly extend the lives of individuals living with ALS.
How similar studies have gone: Previous research initiatives focused on ALS have shown promise in developing effective therapies, indicating that this approach has the potential for success.
Where this research is happening
-
St. Joseph's Hospital and Medical Center
Phoenix, United States Active
Researchers
- Principal investigator: Bowser, Robert P — St. Joseph's Hospital and Medical Center
- Study coordinator: Bowser, Robert P
Related research
Other NIH-funded projects on the same topics.
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Access for All in ALS: West Coordinating Center for ALS patient care and research
A national ALS research network is building a West Coast coordinating center to collect and study high-quality patient samples and data to speed better ALS therapies.
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South African Manganese Exposure and Brain Health in a Long-Term Cohort
A study in an African community exposed to manganese pollution aims to understand whether exposure accelerates motor and thinking problems over time, with potential to guide protections for affected residents.
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Brain network problems tied to memory and thinking in adults with Down syndrome
This project looks at why key brain cells and networks that support memory and self-awareness break down in adults with Down syndrome.
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Manganese Pollution and Brain Health in African Communities
This grant studies whether environmental manganese exposure from a large South African smelter is linked to worsening motor and cognitive health in a defined African cohort.
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Access for All in ALS — West Coordinating Center
This project builds a national network to collect clinical data and patient samples to speed development of new treatments for people living with ALS.
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Microglia's role in C9orf72-linked ALS and frontotemporal dementia
This work looks at whether immune cells in the brain called microglia drive nerve-cell and synapse loss in people with C9orf72-related ALS and frontotemporal dementia.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.