Improving access to long-acting HIV prevention methods for young women in Africa

Scaling Comprehensively Access to Long-acting for an Effective Use of PrEP (SCALE-UP)

['FUNDING_R21'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-11006907

This study is looking at how to make it easier for young women and girls in Africa to use a long-lasting HIV prevention shot called cabotegravir, so they can stay healthy and safe from HIV.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MARYLAND BALTIMORE (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-11006907 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing the implementation of long-acting injectable cabotegravir (CAB-LA) as a preventive measure against HIV among adolescent girls and young women in Africa. It aims to understand the real-world application of CAB-LA within Zambia's national HIV program, assessing factors that influence its uptake and effectiveness. By employing a rigorous implementation science approach, the study seeks to identify barriers and facilitators to accessing this innovative prevention method, ultimately aiming to improve health outcomes for at-risk populations.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescent girls and young women in Africa, particularly those at high risk for HIV.

Not a fit: Patients who are not at risk for HIV or those who do not reside in the targeted geographic areas may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce HIV infection rates among adolescent girls and young women in Africa.

How similar studies have performed: Previous research has shown promising results with long-acting PrEP modalities in controlled settings, but this study aims to explore their effectiveness in real-world applications, making it a novel approach.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome, Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.