Improving access to HIV prevention for rural people who inject drugs

Optimizing PrEP Care Delivery through Adaptive Intervention Strategies for Underserved Rural People who Inject Drugs

['FUNDING_R01'] · UNIVERSITY OF KENTUCKY · NIH-11037395

This study is all about finding better ways to help people who inject drugs in rural areas get and stay on PrEP, a medication that helps prevent HIV, by offering personalized support and care.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF KENTUCKY (nih funded)
Locations1 site (LEXINGTON, UNITED STATES)
Trial IDNIH-11037395 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing the delivery of Pre-Exposure Prophylaxis (PrEP) care to underserved rural populations, particularly people who inject drugs (PWID). It aims to address barriers to PrEP uptake through adaptive intervention strategies, building on previous successful pilot interventions in Kentucky's Appalachian region. The study will implement and evaluate new approaches to increase the number of PWID who initiate and continue PrEP, thereby reducing the risk of HIV transmission. Participants will receive support through case management and tailored interventions designed to meet their specific needs.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living in rural areas who inject drugs and are at risk for HIV.

Not a fit: Patients who do not inject drugs or those who are already engaged in effective HIV prevention strategies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly increase PrEP uptake among rural PWID, leading to a reduction in new HIV infections.

How similar studies have performed: Previous pilot interventions in this region have shown promising results in improving PrEP care delivery for PWID, indicating a potential for success with these new strategies.

Where this research is happening

LEXINGTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.