Improving access to HIV prevention for people who inject drugs

SAIA-PrEP: a systems analysis and improvement approach to optimize PrEP implementation in syringe service programs

NIH-funded research University of California, San Diego · NIH-10866452

This study is looking at ways to make it easier for people who inject drugs to get and use PrEP, a medication that helps prevent HIV, by working with syringe service programs to find and fix any obstacles they face.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-10866452 on NIH RePORTER

What this research studies

This research focuses on enhancing the implementation of pre-exposure prophylaxis (PrEP) for individuals who inject drugs (PWID) through syringe service programs (SSPs). It aims to identify and address barriers to PrEP access and uptake by utilizing a systematic approach called the Systems Analysis and Improvement Approach (SAIA). The study will involve 32 SSPs, which will be divided into two groups: one receiving the SAIA intervention and the other continuing with standard practices. By analyzing and improving the delivery of PrEP services, the research seeks to increase the number of PWID who can effectively access this vital HIV prevention method.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who inject drugs and are at risk of HIV infection.

Not a fit: Patients who do not inject drugs or are not at risk for HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly increase PrEP access and uptake among people who inject drugs, thereby reducing HIV incidence in this vulnerable population.

How similar studies have performed: Previous research has shown that targeted interventions in similar settings can improve access to HIV prevention services, indicating potential for success with this approach.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.