NIH-funded research NIH-funded research

Improving a tool to analyze how climate change affects brain health in older adults

Official title: Enhancing SPACE, an innovative python package to account for spatial confounding used to estimate climate-sensitive events among older Medicare

Funded at Yale University · NIH-10839707 · Data updated 2026-11-12

This study is looking at how things like air pollution and heat from climate change affect the health of older adults with Alzheimer's and similar conditions, and it aims to create a helpful tool to better understand these risks so we can protect their health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startDecember 15, 2022
Project endNovember 30, 2025
Funding year2023
Award (this year)$262,689
NIH project number3RF1AG080948-01S1
Project IDNIH-10839707 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults, particularly those with Alzheimer's disease or related dementias, who may be affected by environmental factors like air pollution.

Less likely to help

Patients who are younger or do not have Alzheimer's disease or related dementias may not benefit from this research.

What this research studies

This research focuses on understanding how climate change, particularly air pollution and heat, impacts the health of older adults with Alzheimer's disease and related dementias. By developing a specialized software tool, the researchers aim to better estimate the effects of environmental factors on hospital admissions and mortality rates among this vulnerable population. The study will analyze various data sources to account for different factors that may influence these health outcomes, ensuring a more accurate understanding of the risks involved. Ultimately, the goal is to provide clearer guidelines for addressing the health impacts of climate change on older adults.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for protecting the brain health of older adults in the face of climate change.

How similar studies have gone: Previous research has indicated links between environmental factors and brain health, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Bell, Michelle L — Yale University
  • Study coordinator: Bell, Michelle L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.