Improving a technology for measuring the mass of complex biological samples
Official title: Advancing High-Resolution Charge Detection-Mass Spectrometry
Funded at Trustees of Indiana University · NIH-10944800 · Data updated 2026-11-12
This study is working on improving a special technology that helps scientists measure tiny particles in biological samples more accurately and quickly, which could lead to better understanding and treatment of different diseases that affect patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Trustees of Indiana University NIH-funded |
| Lab location | 1 site (Bloomington, United States) |
| Project start | September 24, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $265,939 |
| NIH project number | 1R01GM155650-01 |
| Project ID | NIH-10944800 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that require precise biological analysis, such as genetic disorders or viral infections.
✕Less likely to help
Patients with conditions that do not involve complex biological sample analysis may not receive benefit from this research.
What this research studies
This research focuses on advancing charge detection mass spectrometry (CD-MS), a technology that accurately measures the mass of complex biological samples. By simultaneously measuring the mass-to-charge ratio and charge of individual ions, researchers aim to enhance the precision and speed of these measurements. The project addresses current limitations in resolving power and measurement time, utilizing computer simulations to design improved detection systems. Patients may benefit from advancements in understanding biological markers and treatments related to various diseases.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnostics and treatments for diseases by improving the analysis of biological samples.
How similar studies have gone: While charge detection mass spectrometry is a developing field, similar approaches have shown promise in enhancing the accuracy of mass spectrometry techniques.
Where this research is happening
-
Trustees of Indiana University
Bloomington, United States Active
Researchers
- Principal investigator: Jarrold, Martin F — Trustees of Indiana University
- Study coordinator: Jarrold, Martin F
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.