Improving 3D imaging of cells and tissues using advanced cutting technology
Official title: Acquisition of a Leica ARTOS 3D Ultramicrotome
Funded at Vanderbilt University · NIH-10986250 · Data updated 2026-11-12
This study is all about making it easier and more accurate for researchers at Vanderbilt University to prepare tiny tissue samples for detailed imaging, helping them better understand cellular structures.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project start | July 1, 2024 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $139,393 |
| NIH project number | 1R24OD037694-01 |
| Project ID | NIH-10986250 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include researchers and clinicians working on cellular biology, cancer biology, and other fields requiring advanced imaging techniques.
✕Less likely to help
Patients who are not involved in research or do not require advanced imaging for their medical conditions may not receive any direct benefit from this research.
What this research studies
This research focuses on enhancing the preparation of samples for Electron Microscopy (EM) by acquiring a Leica ARTOS Ultramicrotome. The ultramicrotome will automate the process of cutting tissue samples into ultra-thin sections, which is crucial for creating detailed 3D images of cellular structures. By streamlining this process, the research aims to reduce errors and improve efficiency in imaging workflows for various biological studies. The facility will provide these advanced imaging services to researchers at Vanderbilt University and its medical center.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and efficient imaging of cellular structures, benefiting a wide range of biological and medical research.
How similar studies have gone: Other research has successfully utilized automated cutting technologies in electron microscopy, indicating a promising approach for improving imaging techniques.
Where this research is happening
-
Vanderbilt University
Nashville, United States Active
Researchers
- Principal investigator: Krystofiak, Evan — Vanderbilt University
- Study coordinator: Krystofiak, Evan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.