Improving 3D imaging for better cancer detection

Reconstruction-free three dimensional positron emission imaging

NIH-funded research University of California at Davis · NIH-10895310

This study is testing a new way to take clearer images of cancer using advanced technology that helps doctors see tumors more accurately while keeping radiation exposure low for patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-10895310 on NIH RePORTER

What this research studies

This research focuses on enhancing positron emission imaging (PEI) by utilizing advanced time-of-flight (TOF) technology to achieve high-resolution images without the need for reconstruction algorithms. By measuring the differences in TOF of annihilation photons from radiotracers, the project aims to localize positron emitters with unprecedented accuracy. This could lead to significant improvements in image quality, allowing for better detection and staging of cancers while reducing radiation exposure for patients. The study will develop a proof-of-concept imaging system to validate these advancements.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients undergoing imaging for cancer diagnosis or staging.

Not a fit: Patients with conditions that do not require imaging or those who are not candidates for positron emission tomography may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate cancer imaging, improving diagnosis and treatment planning for patients.

How similar studies have performed: Previous research has shown promise in enhancing imaging techniques, but this approach is considered novel and untested at this level of resolution.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer Staging
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.