NIH-funded research Sbir 1 grant

Improving 3D imaging analysis for dental and facial surgeries

Official title: CraniaMap: Joint Solution for Auto-Segmentation and Landmarking from CBCT Scans

Funded at Ther-Ai LLC · NIH-11006192 · Data updated 2026-11-12

This study is testing a new software called CraniaMap that helps doctors better analyze 3D scans of your head and face, making it easier for them to plan orthodontic and facial surgeries, especially when dealing with unique anatomical features.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionTher-Ai LLC
NIH-funded
Lab location1 site (Kissimmee, UNITED STATES)
Project startApril 1, 2025
Project endDecember 31, 2025
Funding year2025
Award (this year)$306,633
NIH project number1R43DE034322-01
Project IDNIH-11006192 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients requiring orthodontic treatment or craniomaxillofacial surgeries who would benefit from enhanced imaging analysis.

Less likely to help

Patients who do not require surgical intervention or imaging analysis for orthodontic or craniomaxillofacial conditions may not benefit from this research.

What this research studies

This research focuses on enhancing the analysis of cone beam computed tomography (CBCT) scans, which are crucial for planning orthodontic and craniomaxillofacial surgeries. The team at Ther-AI LLC is developing a software called CraniaMap that utilizes advanced artificial intelligence to improve the accuracy and efficiency of auto-segmentation and landmarking in these scans. By addressing the challenges of managing complex 3D data, this project aims to provide healthcare professionals with better tools for personalized patient care and treatment planning. The approach includes using a self-supervised learning model to improve segmentation performance, particularly in cases with anatomical variations.

Why it matters

Potential benefit: If successful, this research could lead to more precise and efficient surgical planning, ultimately improving patient outcomes in orthodontics and reconstructive surgeries.

How similar studies have gone: Previous research has shown promise in using AI for medical imaging, indicating that this approach could lead to significant advancements in the field.

Where this research is happening

  • Ther-Ai LLC
    Kissimmee, United States
    Active

Researchers

  • Principal investigator: Han, Wade — Ther-Ai LLC
  • Study coordinator: Han, Wade

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.