Impact of vascular risk factors on dementia and stroke in older adults with late-onset epilepsy
Official title: Effects of vascular risk factors on risk for dementia and stroke after late-onset epilepsy (EpilepsyCOG)
Funded at Columbia University Health Sciences · NIH-11049120 · Data updated 2026-11-12
This study is looking at how things like high blood pressure and cholesterol might affect older adults with late-onset epilepsy, helping us understand their risk for dementia and stroke, so we can find better ways to keep their brains healthy and improve their care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2022 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $680,886 |
| NIH project number | 5R01AG074355-04 |
| Project ID | NIH-11049120 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults aged 65 and above who have been diagnosed with late-onset epilepsy.
✕Less likely to help
Patients who are younger than 65 or do not have a diagnosis of late-onset epilepsy may not benefit from this research.
What this research studies
This research investigates how vascular risk factors contribute to the risk of developing dementia and stroke in older adults diagnosed with late-onset epilepsy, which occurs at age 65 or older. The study aims to identify the relationship between these risk factors and cognitive decline, focusing on improving patient care by integrating risk assessments into epilepsy management. By analyzing data from individuals with late-onset epilepsy, the research seeks to develop effective prevention strategies to mitigate these risks. The ultimate goal is to enhance brain health and cognitive function in this vulnerable population.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies for dementia and stroke in older adults with late-onset epilepsy.
How similar studies have gone: Previous research has indicated that vascular risk factors significantly impact cognitive decline and stroke, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Columbia University Health Sciences
New York, United States Active
Researchers
- Principal investigator: Choi, Hyunmi — Columbia University Health Sciences
- Study coordinator: Choi, Hyunmi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.