Impact of vaping tobacco and cannabis on oral bacteria and fungi

Effect of aerosolized tobacco and cannabis products on Streptococcus mutans and Candida albicans interkingdom cariogenicity

NIH-funded research University of California Los Angeles · NIH-10952794

This study looks at how vaping tobacco and cannabis might affect the growth of bad germs in the mouth, especially in teens and young adults who are using these products more often, to help understand the potential risks to their oral health.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10952794 on NIH RePORTER

What this research studies

This research investigates how vaping tobacco and cannabis products affects the growth of harmful oral bacteria and fungi, specifically Streptococcus mutans and Candida albicans. It focuses on adolescents and young adults, a demographic increasingly using electronic nicotine delivery devices. The study will analyze the differences in effects between pure nicotine and nicotine-containing vape aerosols, as well as the impact of tetrahydrocannabinol (THC) on these microorganisms. By understanding these interactions, the research aims to shed light on the oral health risks associated with vaping.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents and young adults who use electronic nicotine delivery devices or cannabis products.

Not a fit: Patients who do not use vaping products or are not within the adolescent to young adult age range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prevention strategies and treatments for dental caries in young people who use vaping products.

How similar studies have performed: While there is emerging evidence regarding the effects of nicotine and THC on oral health, this specific approach focusing on vape aerosols is relatively novel and has not been extensively tested.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.