Impact of vaccination on respiratory infections in organ transplant patients
Effects of Vaccination on Acute and Post-Acute Respiratory Viral Infection Outcomes in Solid Organ Transplant Recipients
This study looks at how well vaccines work to protect people who have had organ transplants from serious respiratory infections like COVID-19, helping to ensure they stay healthy despite their weakened immune systems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11108605 on NIH RePORTER |
What this research studies
This research investigates how vaccinations affect the outcomes of respiratory viral infections, such as COVID-19, in solid organ transplant recipients. It focuses on understanding the risks these patients face due to their immunosuppressed state and chronic health issues. The study aims to assess the effectiveness of vaccines in preventing severe infections and post-acute complications that can arise after viral infections. By analyzing patient responses to vaccination, the research seeks to improve health outcomes for this vulnerable population.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have received solid organ transplants and are at risk for respiratory viral infections.
Not a fit: Patients who have not undergone solid organ transplantation or those who are not at risk for respiratory viral infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccination strategies that significantly enhance the health and recovery of organ transplant recipients after respiratory viral infections.
How similar studies have performed: Previous research has shown promising results in improving outcomes for immunocompromised patients through vaccination, indicating that this approach may be effective.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Werbel, William — Johns Hopkins University
- Study coordinator: Werbel, William
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.