Impact of prenatal alcohol exposure on Alzheimer's disease symptoms
Effects of Prenatal Alcohol Exposure on Alzheimer's Disease-associated Neuropsychiatric Symptoms
This study is looking at how drinking alcohol during pregnancy might affect brain health and behavior later in life, especially for people who may develop Alzheimer's disease, and it hopes to find ways to help those who are at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10912554 on NIH RePORTER |
What this research studies
This research investigates how prenatal alcohol exposure (PAE) may influence the development of neuropsychiatric symptoms associated with Alzheimer's disease (AD). It aims to understand the interactions between genetic factors related to AD and environmental factors like PAE, focusing on how these factors affect brain function and behavior. The study will explore the underlying neuronal mechanisms and potential treatments for cognitive impairments in affected individuals. By examining these interactions at various biological levels, the research seeks to provide insights into prevention and management strategies for those at risk.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals under 21 years old who have a history of prenatal alcohol exposure and exhibit symptoms related to Alzheimer's disease.
Not a fit: Patients who do not have a history of prenatal alcohol exposure or do not exhibit neuropsychiatric symptoms related to Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals affected by both prenatal alcohol exposure and Alzheimer's disease.
How similar studies have performed: While the specific interactions between prenatal alcohol exposure and Alzheimer's disease are less explored, related research has shown promising results in understanding the effects of environmental factors on neurodevelopmental outcomes.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Ma, Yao-Ying — Indiana University Indianapolis
- Study coordinator: Ma, Yao-Ying
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.