Impact of parenthood on health in people with cystic fibrosis
Official title: Health Outcomes of Parents with Cystic Fibrosis (HOPe:CF)
Funded at University of Pittsburgh at Pittsburgh · NIH-11010760 · Data updated 2026-11-12
This study looks at how becoming a parent affects the health of people with cystic fibrosis, especially their lung function, by comparing new parents to those who aren't parents, to help guide future parents with CF in making informed choices about having kids.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | February 1, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $552,917 |
| NIH project number | 5R01HL161164-03 |
| Project ID | NIH-11010760 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with cystic fibrosis who are considering or have recently become parents.
✕Less likely to help
Patients without cystic fibrosis or those who are not planning to become parents may not benefit from this research.
What this research studies
This research investigates how becoming a parent affects the health of individuals with cystic fibrosis (CF), particularly focusing on lung function changes before and after parenthood. By analyzing data from the Cystic Fibrosis Foundation Patient Registry and surveys from new parents, the study aims to identify health outcomes associated with parenthood in the context of new CF treatments. The research will compare the health of new parents with that of non-parents to understand the implications of parenthood on pulmonary health. This information will help inform reproductive decisions and guide interventions for those with CF considering parenthood.
Why it matters
Potential benefit: If successful, this research could provide valuable insights that improve health management and support for parents with cystic fibrosis.
How similar studies have gone: Other research has shown promising results in understanding health outcomes in chronic conditions, making this approach both relevant and potentially impactful.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Kazmerski, Traci — University of Pittsburgh at Pittsburgh
- Study coordinator: Kazmerski, Traci
Related research
Other NIH-funded projects on the same topics.
-
Health outcomes for parents living with cystic fibrosis
This project looks at how becoming a parent affects the health and lung function of people with cystic fibrosis now that powerful CFTR modulator drugs are widely used.
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Pharmacogenomic Predictors of Clinical Responses in Cystic Fibrosis using Targeted WGS
A study looking at how genetic information from whole-genome sequencing can predict how people with cystic fibrosis respond to medications, using a focused set of pharmacogenomic genes.
-
Ceftaroline-meropenem combo to beat MRSA in cystic fibrosis
A new combination antibiotic approach is being tested to help people with cystic fibrosis who have MRSA infections that resist standard treatments.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.