NIH-funded research NIH-funded research

Impact of overload and overuse after subscapularis tears on shoulder health

Official title: Impact of Overload and Overuse Following Subscapularis Tears: Mechanisms of Shoulder Joint Damage

Funded at Philadelphia VA Medical Center · NIH-11493627 · Data updated 2026-11-12

This project looks at how tears in the subscapularis tendon can damage the shoulder joint over time, potentially guiding better care for people with this common injury.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPhiladelphia VA Medical Center
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startNovember 1, 2022
Project endOctober 31, 2027
Funding year2027
NIH project number5I01RX003652-05
Project IDNIH-11493627 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are individuals with diagnosed subscapularis tendon tears or shoulder injuries related to rotator cuff damage.

Less likely to help

Patients without subscapularis tears or without a condition affecting the shoulder joint may have limited direct benefit.

What this research studies

People with rotator cuff tears often develop painful, crippling changes in shoulder movement as the joint mechanics shift. The researchers will study how subscapularis tears affect the shoulder joint using data from laboratory models and prior findings about how tears alter force balance and cause cartilage and tendon damage. The goal is to uncover the mechanisms driving progressive joint damage so clinicians can choose treatments that minimize long-term harm. This work builds on previous models and aims to translate those insights toward improved clinical care for patients with subscapularis tears.

Why it matters

Potential benefit: Gaining clearer guidance on how subscapularis tears cause joint damage could lead to earlier, more effective treatments and better long-term shoulder function for patients.

How similar studies have gone: Previous research has shown that tear-induced changes in shoulder mechanics can drive joint damage, supporting the relevance of this approach.

Where this research is happening

  • Philadelphia VA Medical Center
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Kuntz, Andrew Frederic — Philadelphia VA Medical Center
  • Study coordinator: Kuntz, Andrew Frederic

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.