Impact of limited sleep on blood pressure in children of hypertensive parents
Official title: Effects of Experimental Sleep Restriction in Offspring of Hypertensive Parents
Funded at Mayo Clinic Rochester · NIH-11078243 · Data updated 2026-11-12
This study is looking at how not getting enough sleep affects blood pressure and heart health in young people under 21 who have a family history of high blood pressure, to see if they are at greater risk when they don’t sleep well.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $669,585 |
| NIH project number | 5R01HL169320-02 |
| Project ID | NIH-11078243 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals under 21 years old with a parental history of hypertension.
✕Less likely to help
Patients without a family history of hypertension may not benefit from the findings of this research.
What this research studies
This research investigates how sleep restriction affects blood pressure and cardiovascular function in individuals under 21 years old who have a family history of hypertension. The study will involve a controlled environment where participants will experience both normal sleep and restricted sleep over a 10-day period. By comparing the effects on those with hypertensive parents to those without, the research aims to understand the heightened risks associated with sleep deficiency in vulnerable populations. Participants will undergo monitoring to assess changes in blood pressure and cardiovascular health during the different sleep conditions.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of blood pressure in young individuals at risk due to their family history.
How similar studies have gone: Previous research has indicated that sleep deprivation can negatively impact cardiovascular health, suggesting that this study's approach is grounded in established findings.
Where this research is happening
-
Mayo Clinic Rochester
Rochester, United States Active
Researchers
- Principal investigator: Covassin, Naima — Mayo Clinic Rochester
- Study coordinator: Covassin, Naima
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.