Impact of intensive medical treatment on heart health in women with non-obstructive coronary artery disease
Effect of Intensive Medical Treatment on Quantified Coronary Artery Plaque Components with Serial Coronary CTA in Women with Non-Obstructive CAD
This study is looking at how a special treatment with medications like aspirin and statins can help improve heart health in women who have symptoms of coronary artery disease but don’t have any blockages, and it aims to see how these treatments affect heart health over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10685609 on NIH RePORTER |
What this research studies
This research investigates how intensive medical treatment can improve heart health in women who have symptoms of coronary artery disease but do not have obstructive blockages. The study involves administering a combination of medications, including aspirin and statins, to evaluate their effects on heart-related events. Researchers will use advanced imaging techniques to monitor changes in coronary artery plaque and blood flow over time. By focusing on women, the study aims to address a significant gap in cardiovascular care for this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing ischemic symptoms but diagnosed with non-obstructive coronary artery disease.
Not a fit: Patients with obstructive coronary artery disease or those not experiencing ischemic symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that significantly reduce heart-related complications in women with non-obstructive coronary artery disease.
How similar studies have performed: Previous research has shown promising results with intensive medical treatment in similar populations, indicating potential for success in this study.
Where this research is happening
Los Angeles, United States
- Cedars-Sinai Medical Center — Los Angeles, United States (Active)
Researchers
- Principal investigator: Dey, Damini — Cedars-Sinai Medical Center
- Study coordinator: Dey, Damini
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.