Impact of heavy metals on intestinal health
Heavy metals exposure regulates secretory lineage in intestinal injury
['FUNDING_R01'] · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · NIH-10804040
This study looks at how being around heavy metals from old uranium mines might impact gut health, especially for people living nearby, by exploring how these toxins can lead to inflammation and a higher chance of developing colorectal cancer.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR (nih funded) |
| Locations | 1 site (ALBUQUERQUE, UNITED STATES) |
| Trial ID | NIH-10804040 on ClinicalTrials.gov |
What this research studies
This research investigates how exposure to heavy metals, particularly from abandoned uranium mine sites, affects the health of the intestines. It focuses on understanding the molecular changes in intestinal cells that occur due to chronic exposure to these environmental toxins. By analyzing the effects of uranium-bearing dust on intestinal epithelial cells, the study aims to uncover the mechanisms behind intestinal inflammation and increased risk of colorectal cancer. Patients living near contaminated sites may experience these health issues, and the research seeks to provide insights into potential interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living near abandoned uranium mine sites who may be experiencing intestinal health issues.
Not a fit: Patients who do not live in areas affected by heavy metal contamination are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for intestinal diseases linked to heavy metal exposure.
How similar studies have performed: Previous research has shown that environmental toxins can significantly impact intestinal health, suggesting that this study's approach could yield valuable insights.
Where this research is happening
ALBUQUERQUE, UNITED STATES
- UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR — ALBUQUERQUE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: IN, JULIE GOEUN — UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
- Study coordinator: IN, JULIE GOEUN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.