Impact of estrogen therapy on health issues in postmenopausal women with HIV

Effect of estrogen replacement on postmenopausal ART-associated comorbidity and viral latency

NIH-funded research Oregon Health & Science University · NIH-11076821

This study is looking at how estrogen replacement therapy might help improve health issues related to aging, like weight gain and diabetes, in women living with HIV after menopause, to find better ways to support their overall health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOregon Health & Science University NIH-funded
Lab location1 site (Portland, United States)
Project IDNIH-11076821 on NIH RePORTER

What this research studies

This research investigates how estrogen replacement therapy may affect health complications associated with aging in women living with HIV, particularly after menopause. It focuses on understanding the relationship between estrogen deficiency and various age-related diseases, such as obesity and diabetes, in this population. The study aims to explore how estrogen therapy could potentially improve metabolic health and reduce chronic inflammation linked to antiretroviral therapy. By examining these factors, the research seeks to provide insights into better management strategies for postmenopausal women with HIV.

Who could benefit from this research

Good fit: Ideal candidates for this research are postmenopausal women living with HIV who are experiencing age-associated health complications.

Not a fit: Patients who are not postmenopausal or those who do not have HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes and quality of life for postmenopausal women living with HIV by addressing age-related health issues.

How similar studies have performed: Previous research has shown promising results in addressing age-related health issues in women with HIV, but this specific approach focusing on estrogen therapy is relatively novel.

Where this research is happening

Portland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.